The opening situation is fictional. It illustrates possible symptoms, not a specific patient or every clinical course, and it cannot be used to make a diagnosis.
It is five in the morning, several days after childbirth. A mother has barely slept, speaks unusually quickly and begins to hear messages intended only for her in ordinary sounds. She experiences them as urgent reality, not as an idea she can simply set aside.
This picture may resemble some presentations of postpartum psychosis, but similar symptoms can have other causes. Sudden delusions, hallucinations, severe confusion or manic behaviour after childbirth require urgent professional assessment. NICE treats suspected postpartum psychosis as a severe acute condition requiring immediate assessment; an immediate danger calls for emergency medical help.
1. There is no single presentation or established single mechanism
Postpartum psychosis is a term for severe episodes that usually begin abruptly in the first weeks after childbirth. They may involve mania, depression or mixed mood, confusion, delusions and hallucinations. Symptoms differ between people and can change rapidly.
Some research frameworks explain psychotic experiences through altered salience or predictive processing. These models help generate hypotheses; they are not a proven single mechanism of postpartum psychosis.
A person with psychosis may have partial or absent insight into their condition. Insight varies over time and between patients. It is therefore inaccurate to say that every person with psychosis always treats every experience as unquestionable fact.
2. What reviews of the evidence show
Rare but severe
A 2021 review reports roughly one to two cases per thousand births. This is a pooled estimate; frequency varies with definitions, populations and case detection.

Bipolar spectrum and previous episodes
Bipolar disorder and a previous episode of postpartum psychosis are among the best-supported risk factors. One characteristic alone cannot determine an individual’s risk.
Hormones, sleep, immunity and genetics
Research considers their interaction. The causal pathway is unsettled; the sleep review, for example, says it is unclear whether sleep disturbance is a symptom, a trigger or both.
3. What was measured — and what was not
The cited sources are mainly reviews and clinical syntheses, not experiments that randomly assigned women a biological “trigger”. They can summarize occurrence, timing, clinical presentation and associated risk factors. They do not prove a simple claim such as “a hormonal fall caused this particular act”.
The immune evidence requires the same caution. The review describes emerging evidence of possible immune involvement while stressing that observed changes may be causes, consequences or accompanying phenomena.
Postpartum psychosis is not a biological story with one switch. It is a clinical condition whose origin probably involves several interacting factors.
— Editorial summary4. Medical explanation, moral judgement and law
Psychotic symptoms may materially impair perception, judgement and behavioural control. That does not establish the extent of impairment in a particular person without an individual assessment.

This article describes a medical and psychological framework. It is not a legal test of criminal responsibility under Czech law. A legal conclusion requires expert and judicial assessment of the particular act, mental state and evidence. A diagnosis is neither a verdict nor an automatic excuse.
5. What this article claims — and what it does not
Postpartum psychosis is a rare acute condition that can severely disrupt mood, thought and contact with reality and requires rapid professional help.

A short narrative cannot establish a diagnosis, a single biological cause, or the moral or legal responsibility of a particular person.
6. What would weaken the main explanation?
The multifactorial account would be weakened by repeated prospective studies across populations that identified one independent mechanism with high predictive accuracy while excluding meaningful roles for sleep, genetic vulnerability, immunity and other factors. Current reviews do not show such a result.
The most accurate answer is sometimes not “we know why it happened”, but “we know the condition can be acute and dangerous, while its precise cause and the degree of responsibility must be assessed separately”.
— Jiný Kontext
